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Superoxide inhibition restores endothelium-dependent dilatation in aging arteries by enhancing impaired adherens junctions
Endothelium-dependent, nitric oxide-mediated dilatation is impaired in aging arteries. The dysfunction reflects increased production of reactive oxygen species (ROS), is reversed by inhibiting superoxide with superoxide dismutase (SOD) mimics, and is assumed to reflect superoxide-mediated inactivati...
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| Gepubliceerd in: | Am J Physiol Heart Circ Physiol |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6048466/ https://ncbi.nlm.nih.gov/pubmed/29351453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00681.2017 |
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