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Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex
Repair of interstrand crosslinks by the Fanconi anemia (FA) pathway requires both the monoubiquitination and de-ubiquitination of the FANCI/FANCD2 (FANCI/D2) complex. In the standing model, the phosphorylation of six sites in the FANCI S/TQ cluster domain occurs upstream of, and promotes, FANCI/D2 m...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538132/ https://ncbi.nlm.nih.gov/pubmed/28636932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.081 |
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