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Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers
Fanconi anemia (FA), the most common form of inherited bone marrow failure, predisposes to leukemia and solid tumors. FA is caused by the genetic disruption of a cellular pathway that repairs DNA interstrand crosslinks. The impaired function of this pathway, and the genetic instability that results,...
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| Veröffentlicht in: | Int J Hematol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5904331/ https://ncbi.nlm.nih.gov/pubmed/28631178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-017-2283-4 |
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