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Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors.

In our earlier studies we demonstrated that in HeLaM cells, interferon-alpha produces two functionally distinguishable signals, both of which are needed for induced transcription of mRNA 561 and other inducible mRNAs. Interferon-gamma cannot induce mRNA 561 because it produces only signal 1. Here we...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Tiwari, R K, Kusari, J, Sen, G C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2828026/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb02659.x
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