GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasiveness

GATA binding protein 3 (GATA3) is indispensable in development of human organs. However, the role of GATA3 in cancers remains elusive. Hypoxia inducible factor (HIF)-1 plays an important role in pathogenesis of human cancers. Regulation of HIF-1α degradation is orchestrated through collaboration of...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Lin, M-C, Lin, J-J, Hsu, C-L, Juan, H-F, Lou, P-J, Huang, M-C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537608/
https://ncbi.nlm.nih.gov/pubmed/28263977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.8
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