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SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer

Pancreatic cancer has a devastating prognosis, with an overall 5-year survival rate of ~8%, restricted treatment options and characteristic molecular heterogeneity. SerpinB2 expression, particularly in the stromal compartment, is associated with reduced metastasis and prolonged survival in pancreati...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Harris, N L E, Vennin, C, Conway, J R W, Vine, K L, Pinese, M, Cowley, M J, Shearer, R F, Lucas, M C, Herrmann, D, Allam, A H, Pajic, M, Morton, J P, Biankin, A V, Ranson, M, Timpson, P, Saunders, D N
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537606/
https://ncbi.nlm.nih.gov/pubmed/28346421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.63
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