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Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

The highly conserved Wnt signaling pathway regulates cell proliferation and differentiation in vertebrates and invertebrates. Upon binding of a Wnt ligand to a receptor of the Fz family, Disheveled (Dsh/Dvl) transduces the signal during canonical and non-canonical Wnt signaling. The specific details...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kaur, Prameet, Lam, Vanessa Yuk Man, Mannava, Anirudh Gautam, Suresh, Jahnavi, Jenny, Andreas, Tolwinski, Nicholas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537288/
https://ncbi.nlm.nih.gov/pubmed/28761148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04414-0
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