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Application of optogenetic Amyloid-β distinguishes between metabolic and physical damages in neurodegeneration
The brains of Alzheimer’s disease patients show a decrease in brain mass and a preponderance of extracellular Amyloid-β plaques. These plaques are formed by aggregation of polypeptides that are derived from the Amyloid Precursor Protein (APP). Amyloid-β plaques are thought to play either a direct or...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145416/ https://ncbi.nlm.nih.gov/pubmed/32228858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52589 |
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