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Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins

Secreted signaling proteins of the Wnt family are known to regulate a diverse range of developmental processes and their signaling pathway through β-catenin is frequently activated in cancer. The identification of both Frizzled and LRP5/6 proteins as components of cell surface receptors for Wnt prot...

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Detalhes bibliográficos
Main Authors: Brennan, Keith, Gonzalez-Sancho, José M., Castelo-Soccio, Leslie A., Howe, Louise R., Brown, Anthony M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494703/
https://ncbi.nlm.nih.gov/pubmed/15064719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207642
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