Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines

Glioblastoma multiforme (GBM) exhibits high resistance to the standard treatment of temozolomide (TMZ) combined with radiotherapy, due to its remarkable cell heterogeneity. Accordingly, there is a need to target alternative molecules enhancing specific GBM autocrine or paracrine mechanisms and ampli...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Oancea-Castillo, Liliana R., Klein, Carmen, Abdollahi, Amir, Weber, Klaus-Josef, Régnier-Vigouroux, Anne, Dokic, Ivana
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536935/
https://ncbi.nlm.nih.gov/pubmed/28494176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1323583
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