Proteostasis, oxidative stress and aging

The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are necessary which regulate and preserve a functiona...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Korovila, Ioanna, Hugo, Martín, Castro, José Pedro, Weber, Daniela, Höhn, Annika, Grune, Tilman, Jung, Tobias
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536880/
https://ncbi.nlm.nih.gov/pubmed/28763764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.008
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