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Proteostasis, oxidative stress and aging

The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are necessary which regulate and preserve a functiona...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Korovila, Ioanna, Hugo, Martín, Castro, José Pedro, Weber, Daniela, Höhn, Annika, Grune, Tilman, Jung, Tobias
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536880/
https://ncbi.nlm.nih.gov/pubmed/28763764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.008
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