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Proteostasis, oxidative stress and aging

The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are necessary which regulate and preserve a functiona...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Korovila, Ioanna, Hugo, Martín, Castro, José Pedro, Weber, Daniela, Höhn, Annika, Grune, Tilman, Jung, Tobias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536880/
https://ncbi.nlm.nih.gov/pubmed/28763764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.008
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