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Proteostasis, oxidative stress and aging

The production of reactive species is an inevitable by-product of metabolism and thus, life itself. Since reactive species are able to damage cellular structures, especially proteins, as the most abundant macromolecule of mammalian cells, systems are necessary which regulate and preserve a functiona...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Korovila, Ioanna, Hugo, Martín, Castro, José Pedro, Weber, Daniela, Höhn, Annika, Grune, Tilman, Jung, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536880/
https://ncbi.nlm.nih.gov/pubmed/28763764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.008
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