Rac1 mediates STAT3 activation by autocrine IL-6

The activity of the small GTPase, Rac1, plays a role in various cellular processes including cytoskeletal rearrangement, gene transcription, and malignant transformation. In this report constitutively active Rac1 (Rac V12) is shown to stimulate the activation of STAT3, a member of the family of sign...

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Detalles Bibliográficos
Main Authors: Faruqi, Tatjana R., Gomez, Dolores, Bustelo, Xosé R., Bar-Sagi, Dafna, Reich, Nancy C.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC55365/
https://ncbi.nlm.nih.gov/pubmed/11470914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161281298
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