Autocrine IL-6 mediates pituitary tumor senescence

Cellular senescence is a stable proliferative arrest state. Pituitary adenomas are frequent and mostly benign, but the mechanism for this remains unknown. IL-6 is involved in pituitary tumor progression and is produced by the tumoral cells. In a cell autonomous fashion, IL-6 participates in oncogene...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sapochnik, Melanie, Haedo, Mariana R, Fuertes, Mariana, Ajler, Pablo, Carrizo, Guillermo, Cervio, Andrés, Sevlever, Gustavo, Stalla, Günter K., Arzt, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354864/
https://ncbi.nlm.nih.gov/pubmed/27902467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13577
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