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A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription

Transcription of the several hundred of mouse and human Ribosomal RNA (rRNA) genes accounts for the majority of RNA synthesis in the cell nucleus and is the determinant of cytoplasmic ribosome abundance, a key factor in regulating gene expression. The rRNA genes, referred to globally as the rDNA, ar...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Herdman, Chelsea, Mars, Jean-Clement, Stefanovsky, Victor Y., Tremblay, Michel G., Sabourin-Felix, Marianne, Lindsay, Helen, Robinson, Mark D., Moss, Tom
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536353/
https://ncbi.nlm.nih.gov/pubmed/28715449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006899
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