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Programmed Cell Death 1 (PD-1) and Cytotoxic T Lymphocyte-Associated Antigen 4 (CTLA-4) in Viral Hepatitis

Virus-specific cluster of differentiation 8 (CD8+) cytotoxic T cells (CTL) recognize viral antigens presented on major histocompatibility complex (MHC) class I chains on infected hepatocytes, with help from CD4+ T cells. However, this CTL response is frequently weak or undetectable in patients with...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cho, Hyosun, Kang, Hyojeung, Lee, Hwan Hee, Kim, Chang Wook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536007/
https://ncbi.nlm.nih.gov/pubmed/28703774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071517
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