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Expression of immune checkpoint regulators, cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed death-ligand 1 (PD-L1), in female breast carcinomas

BACKGROUND: Immune checkpoint regulators, cytotoxic T lymphocyte antigen 4 (CTLA-4) and the programmed cell death protein-1/programmed death-ligand 1 (PD-1/PD-L1) have emerged as promising new targets for cancer therapeutics. While tumor expression of PD-L1 has been shown to have objective responses...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kassardjian, Ari, Shintaku, Peter I., Moatamed, Neda A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909602/
https://ncbi.nlm.nih.gov/pubmed/29672601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195958
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