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The Application of REDOR NMR to Understand the Conformation of Epothilone B

The structural information of small therapeutic compounds complexed in biological matrices is important for drug developments. However, structural studies on ligands bound to such a large and dynamic system as microtubules are still challenging. This article reports an application of the solid-state...

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Publicat a:Int J Mol Sci
Autors principals: Lee, Jae-Ho, Kim, Moon-Su, Lee, Hyo Won, Lee, Ihl-Young C., Kim, Hyun Kyoung, Kim, Nam Doo, Lee, SangGap, Seo, Hwajeong, Paik, Younkee
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535963/
https://ncbi.nlm.nih.gov/pubmed/28698492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071472
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