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Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells

Disturbances in histone acetyltransferases (HATs) are common in cancers. In urothelial carcinoma (UC), p300 and CBP are often mutated, whereas the GNAT family HATs GCN5 and PCAF (General Control Nonderepressible 5, p300/CBP-Associated Factor) are often upregulated. Here, we explored the effects of s...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Koutsogiannouli, Evangelia A., Wagner, Nicholas, Hader, Christiane, Pinkerneil, Maria, Hoffmann, Michèle J., Schulz, Wolfgang A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535940/
https://ncbi.nlm.nih.gov/pubmed/28678170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071449
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