Histone Deacetylase Inhibitors as Anticancer Drugs

Carcinogenesis cannot be explained only by genetic alterations, but also involves epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic regulation of gene expression and is controlled by the balance between histone deacetylases (HDAC) and histone acetyltransfer...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Eckschlager, Tomas, Plch, Johana, Stiborova, Marie, Hrabeta, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535906/
https://ncbi.nlm.nih.gov/pubmed/28671573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071414
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