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Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers

Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of heparan sulfate proteoglycans (HSPGs) are epigenetically regulated at many levels. As the exact composition of the heparan sulfate portion of the resulting HSPG molecules is criti...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hull, Elizabeth E., Montgomery, McKale R., Leyva, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535854/
https://ncbi.nlm.nih.gov/pubmed/28672878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071361
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