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Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers

Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of heparan sulfate proteoglycans (HSPGs) are epigenetically regulated at many levels. As the exact composition of the heparan sulfate portion of the resulting HSPG molecules is criti...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Hull, Elizabeth E., Montgomery, McKale R., Leyva, Kathryn J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535854/
https://ncbi.nlm.nih.gov/pubmed/28672878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071361
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