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Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers

Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of heparan sulfate proteoglycans (HSPGs) are epigenetically regulated at many levels. As the exact composition of the heparan sulfate portion of the resulting HSPG molecules is criti...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Hull, Elizabeth E., Montgomery, McKale R., Leyva, Kathryn J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535854/
https://ncbi.nlm.nih.gov/pubmed/28672878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071361
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