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Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers

Emerging evidence suggests that the enzymes in the biosynthetic pathway for the synthesis of heparan sulfate moieties of heparan sulfate proteoglycans (HSPGs) are epigenetically regulated at many levels. As the exact composition of the heparan sulfate portion of the resulting HSPG molecules is criti...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Hull, Elizabeth E., Montgomery, McKale R., Leyva, Kathryn J.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535854/
https://ncbi.nlm.nih.gov/pubmed/28672878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071361
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