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Immune Modulating Topical S100A8/A9 Inhibits Growth of Pseudomonas aeruginosa and Mitigates Biofilm Infection in Chronic Wounds

Pseudomonas aeruginosa biofilm maintains and perturbs local host defense, hindering timely wound healing. Previously, we showed that P. aeruginosa suppressed S100A8/A9 of the murine innate host defense. We assessed the potential antimicrobial effect of S100A8/A9 on biofilm-infected wounds in a murin...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Trøstrup, Hannah, Lerche, Christian Johann, Christophersen, Lars, Jensen, Peter Østrup, Høiby, Niels, Moser, Claus
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535852/
https://ncbi.nlm.nih.gov/pubmed/28672877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071359
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