Adjunctive S100A8/A9 Immunomodulation Hinders Ciprofloxacin Resistance in Pseudomonas aeruginosa in a Murine Biofilm Wound Model

OBJECTIVE: Pseudomonas aeruginosa is known to contribute to the pathogenesis of chronic wounds by biofilm-establishment with increased tolerance to host response and antibiotics. The neutrophil-factor S100A8/A9 has a promising adjuvant effect when combined with ciprofloxacin, measured by quantitativ...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Laulund, Anne S., Schwartz, Franziska, Trøstrup, Hannah, Thomsen, Kim, Christophersen, Lars, Calum, Henrik, Ciofu, Oana, Høiby, Niels, Moser, Claus
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072475/
https://ncbi.nlm.nih.gov/pubmed/33912476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.652012
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