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REM sleep selectively prunes and maintains new synapses in development and learning
The functions and underlying mechanisms of rapid eye movement (REM) sleep remain unclear. Here we show that REM sleep prunes newly-formed postsynaptic dendritic spines of layer 5 pyramidal neurons in the mouse motor cortex during development and motor learning. This REM sleep-dependent elimination o...
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| Udgivet i: | Nat Neurosci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535798/ https://ncbi.nlm.nih.gov/pubmed/28092659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4479 |
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