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REM sleep selectively prunes and maintains new synapses in development and learning

The functions and underlying mechanisms of rapid eye movement (REM) sleep remain unclear. Here we show that REM sleep prunes newly-formed postsynaptic dendritic spines of layer 5 pyramidal neurons in the mouse motor cortex during development and motor learning. This REM sleep-dependent elimination o...

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Bibliografske podrobnosti
izdano v:Nat Neurosci
Main Authors: Li, Wei, Ma, Lei, Yang, Guang, Gan, Wenbiao
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535798/
https://ncbi.nlm.nih.gov/pubmed/28092659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4479
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