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REM sleep selectively prunes and maintains new synapses in development and learning

The functions and underlying mechanisms of rapid eye movement (REM) sleep remain unclear. Here we show that REM sleep prunes newly-formed postsynaptic dendritic spines of layer 5 pyramidal neurons in the mouse motor cortex during development and motor learning. This REM sleep-dependent elimination o...

詳細記述

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書誌詳細
出版年:Nat Neurosci
主要な著者: Li, Wei, Ma, Lei, Yang, Guang, Gan, Wenbiao
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535798/
https://ncbi.nlm.nih.gov/pubmed/28092659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4479
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