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Chemical screening in zebrafish for novel biological and therapeutic discovery

Zebrafish chemical screening allows for an in vivo assessment of small molecule modulation of biological processes. Compound toxicities, chemical alterations by metabolism, pharmacokinetic and pharmacodynamic properties, and modulation of cell niches can be studied with this method. Furthermore, zeb...

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Detalhes bibliográficos
Publicado no:Methods Cell Biol
Main Authors: Wiley, D.S., Redfield, S.E., Zon, L.I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535795/
https://ncbi.nlm.nih.gov/pubmed/28129862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mcb.2016.10.004
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