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Swimming into the Future of Drug Discovery: In Vivo Chemical Screens in Zebrafish

In recent years in vivo chemical screening in zebrafish has emerged as a rapid and efficient method to identify lead compounds that modulate specific biological processes. By performing primary screening in vivo, the bioactivity, toxicity, and off-target side effects are determined from the onset of...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Bowman, Teresa V., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712380/
https://ncbi.nlm.nih.gov/pubmed/20166761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100029t
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