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A Chemical Screen to Identify Novel Inhibitors of Fin Regeneration in Zebrafish

We performed a chemical screen to look for novel inhibitors of zebrafish caudal fin regeneration. In a pilot screen, 520 compounds were tested. Two compounds, budesonide and AGN192403, abrogated fin regeneration. One compound in particular, AGN192403, targets the imidazoline receptor, a pathway not...

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Detalhes bibliográficos
Main Authors: Oppedal, Douglas, Goldsmith, Matthew I.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946367/
https://ncbi.nlm.nih.gov/pubmed/20384483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2009.0633
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