A Chemical Screen Identifies Novel Compounds That Overcome Glial-Mediated Inhibition of Neuronal Regeneration

A major barrier to regeneration of CNS axons is the presence of growth-inhibitory proteins associated with myelin and the glial scar. To identify chemical compounds with the ability to overcome the inhibition of regeneration, we screened a novel triazine library, based on the ability of compounds to...

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Bibliografische gegevens
Hoofdauteurs: Usher, Lynn C., Johnstone, Andrea, Ertürk, Ali, Hu, Ying, Strikis, Dinara, Wanner, Ina B., Moorman, Sanne, Lee, Jae-Wook, Min, Jaeki, Ha, Hyung-Ho, Duan, Yuanli, Hoffman, Stanley, Goldberg, Jeffrey L., Bradke, Frank, Chang, Young-Tae, Lemmon, Vance P., Bixby, John L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855497/
https://ncbi.nlm.nih.gov/pubmed/20357120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0302-10.2010
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