Microtubule stabilization reduces scarring and enables axon regeneration after spinal cord injury

Hypertrophic scarring and poor intrinsic axon growth capacity constitute major obstacles for spinal cord repair. These processes are tightly regulated by microtubule dynamics. We found that moderate microtubule stabilization decreased scar formation after spinal cord injury (SCI) in rodents via vari...

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Detalhes bibliográficos
Main Authors: Hellal, Farida, Hurtado, Andres, Ruschel, Jörg, Flynn, Kevin, Umlauf, Martina, Kapitein, Lukas, Strikis, Dinara, Lemmon, Vance, Bixby, John, Hoogenraad, Casper, Bradke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330754/
https://ncbi.nlm.nih.gov/pubmed/21273450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1201148
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