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Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of HSC clones born has been estimated through transplantation, but experimental approaches to assess the absolute number of forming HSCs in a native setting have remained challenging. Here, we applied sin...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Henninger, Jonathan, Santoso, Buyung, Hans, Stefan, Durand, Ellen, Moore, Jessica, Mosimann, Christian, Brand, Michael, Traver, David, Zon, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535785/
https://ncbi.nlm.nih.gov/pubmed/27870830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3444
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