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Hematopoietic stem cell fate is established by the Notch–Runx pathway

Identifying the molecular pathways regulating hematopoietic stem cell (HSC) specification, self-renewal, and expansion remains a fundamental goal of both basic and clinical biology. Here, we analyzed the effects of Notch signaling on HSC number during zebrafish development and adulthood, defining a...

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Detalhes bibliográficos
Main Authors: Burns, Caroline Erter, Traver, David, Mayhall, Elizabeth, Shepard, Jennifer L., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240042/
https://ncbi.nlm.nih.gov/pubmed/16166372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1337005
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