A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence

Defining the genetic pathways essential for hematopoietic stem cell (HSC) development remains a fundamental goal impacting stem cell biology and regenerative medicine. To genetically dissect HSC emergence in the aorta-gonad-mesonephros (AGM) region, we screened a collection of insertional zebrafish...

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Autors principals: Burns, Caroline E., Galloway, Jenna L., Smith, Alexandra C. H., Keefe, Matthew D., Cashman, Timothy J., Paik, Elizabeth J., Mayhall, Elizabeth A., Amsterdam, Adam H., Zon, Leonard I.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700318/
https://ncbi.nlm.nih.gov/pubmed/19332767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-193607
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