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Ligand-Enabled Auxiliary-Free Meta-C‒H Arylation of Phenylacetic Acids
Meta-C‒H arylation of free phenylacetic acid has been realized using 2-carbomethoxynorbornene (NBE-CO(2)Me) as a transient mediator. Both the modified norbornene and the mono-protected 3-amino-2-hydroxypyridine type ligand are crucial for this auxiliary-free meta-C‒H arylation reaction. A series of...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535739/ https://ncbi.nlm.nih.gov/pubmed/28485900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201702686 |
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