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Ligand-Enabled Auxiliary-Free Meta-C‒H Arylation of Phenylacetic Acids

Meta-C‒H arylation of free phenylacetic acid has been realized using 2-carbomethoxynorbornene (NBE-CO(2)Me) as a transient mediator. Both the modified norbornene and the mono-protected 3-amino-2-hydroxypyridine type ligand are crucial for this auxiliary-free meta-C‒H arylation reaction. A series of...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Li, Gen-Cheng, Wang, Peng, Farmer, Marcus E., Yu, Jin-Quan
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535739/
https://ncbi.nlm.nih.gov/pubmed/28485900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201702686
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