Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells

Previously, we reported that treatment with the G9a histone methyltransferase inhibitor BIX01294 causes bone marrow mesenchymal stem cells (MSCs) to exhibit a cardiocompetent phenotype, as indicated by the induction of the precardiac markers Mesp1 and brachyury. Here, we report that combining the hi...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Yang, Jinpu, Kaur, Keerat, Edwards, John G., Eisenberg, Carol A., Eisenberg, Leonard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534312/
https://ncbi.nlm.nih.gov/pubmed/28791052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3464953
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