Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells

Previously, we reported that treatment with the G9a histone methyltransferase inhibitor BIX01294 causes bone marrow mesenchymal stem cells (MSCs) to exhibit a cardiocompetent phenotype, as indicated by the induction of the precardiac markers Mesp1 and brachyury. Here, we report that combining the hi...

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發表在:Stem Cells Int
Main Authors: Yang, Jinpu, Kaur, Keerat, Edwards, John G., Eisenberg, Carol A., Eisenberg, Leonard M.
格式: Artigo
語言:Inglês
出版: Hindawi 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534312/
https://ncbi.nlm.nih.gov/pubmed/28791052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3464953
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