A1- and A2-Selective Adenosine Antagonists: In Vivo Characterization of Cardiovascular Effects

Caffeine, a nonselective adenosine receptor antagonist, 7-methyl-1,3-dipropylxanthine, a purported A2 selective antagonist and a 1,3-dipropyl-8-phenylxanthine amine congener (XAC), an A1 selective antagonist, were evaluated for their in vivo selectivity at A1 vs. A2 adenosine receptors. Blockade of...

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Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Evoniuk, Gary, Jacobson, Kenneth A., Shamim, Mah T., Daly, John W., Wurtman, Richard J.
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534265/
https://ncbi.nlm.nih.gov/pubmed/3656117
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