Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.

It has been suggested that the infectious agents of scrapie and Creutzfeldt-Jakob disease (CJD) are 'prions' constituted by a protease resistant glycopeptide, PrP. To analyze the role of PrP in CJD infectivity we re-evaluated the biochemical characteristics of infectivity. First, when the infectious...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Manuelidis, L, Sklaviadis, T, Manuelidis, E E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3556164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04760.x
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