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Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.

It has been suggested that the infectious agents of scrapie and Creutzfeldt-Jakob disease (CJD) are 'prions' constituted by a protease resistant glycopeptide, PrP. To analyze the role of PrP in CJD infectivity we re-evaluated the biochemical characteristics of infectivity. First, when the infectious...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Manuelidis, L, Sklaviadis, T, Manuelidis, E E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1987
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3556164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04760.x
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