Evidence suggesting that PrP is not the infectious agent in Creutzfeldt-Jakob disease.
It has been suggested that the infectious agents of scrapie and Creutzfeldt-Jakob disease (CJD) are 'prions' constituted by a protease resistant glycopeptide, PrP. To analyze the role of PrP in CJD infectivity we re-evaluated the biochemical characteristics of infectivity. First, when the infectious...
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| Udgivet i: | EMBO J |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3556164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04760.x |
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