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Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5

The human immunodeficiency virus type 1 (HIV-1)/simian immunodeficiency virus (SIV) envelope spike (Env) mediates viral entry into host cells. The V3 loop of the gp120 component of the Env trimer contributes to the coreceptor binding site and is a target for neutralizing antibodies. We used cryo-ele...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Hu, Guiqing, Liu, Jun, Roux, Kenneth H., Taylor, Kenneth A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533903/
https://ncbi.nlm.nih.gov/pubmed/28539445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00134-17
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