DNA Polymerase Beta Participates in Mitochondrial DNA Repair

We have detected DNA polymerase beta (Polβ), known as a key nuclear base excision repair (BER) protein, in mitochondrial protein extracts derived from mammalian tissue and cells. Manipulation of the N-terminal sequence affected the amount of Polβ in the mitochondria. Using Polβ fragments, mitochondr...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Sykora, P., Kanno, S., Akbari, M., Kulikowicz, T., Baptiste, B. A., Leandro, G. S., Lu, H., Tian, J., May, A., Becker, K. A., Croteau, D. L., Wilson, D. M., Sobol, R. W., Yasui, A., Bohr, V. A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533889/
https://ncbi.nlm.nih.gov/pubmed/28559431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00237-17
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