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High-throughput mutagenesis using a two-fragment PCR approach

Site-directed scanning mutagenesis is a powerful protein engineering technique which allows studies of protein functionality at single amino acid resolution and design of stabilized proteins for structural and biophysical work. However, creating libraries of hundreds of mutants remains a challenging...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Heydenreich, Franziska M., Miljuš, Tamara, Jaussi, Rolf, Benoit, Roger, Milić, Dalibor, Veprintsev, Dmitry B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533798/
https://ncbi.nlm.nih.gov/pubmed/28754896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07010-4
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