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High-throughput mutagenesis using a two-fragment PCR approach

Site-directed scanning mutagenesis is a powerful protein engineering technique which allows studies of protein functionality at single amino acid resolution and design of stabilized proteins for structural and biophysical work. However, creating libraries of hundreds of mutants remains a challenging...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Heydenreich, Franziska M., Miljuš, Tamara, Jaussi, Rolf, Benoit, Roger, Milić, Dalibor, Veprintsev, Dmitry B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533798/
https://ncbi.nlm.nih.gov/pubmed/28754896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07010-4
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