Recombinant attenuated Salmonella Typhimurium with heterologous expression of the Salmonella Choleraesuis O-polysaccharide: high immunogenicity and protection

Non-typhoidal Salmonella are associated with gastrointestinal disease worldwide and invasive disease in Africa. We constructed novel bivalent vaccines through the recombinant expression of heterologous O-antigens from Salmonella Choleraesuis in Salmonella Typhimurium. A recombinant Asd(+) plasmid pC...

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Publicado no:Sci Rep
Main Authors: Zhao, Xinxin, Dai, Qinlong, Zhu, Dekang, Liu, Mafeng, Chen, Shun, Sun, Kunfeng, Yang, Qiao, Wu, Ying, Kong, Qingke, Jia, Renyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533773/
https://ncbi.nlm.nih.gov/pubmed/28754982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07689-5
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