Synthesis and delivery of Streptococcus pneumoniae capsular polysaccharides by recombinant attenuated Salmonella vaccines

Streptococcus pneumoniae capsular polysaccharides (CPSs) are major determinants of bacterial pathogenicity. CPSs of different serotypes form the main components of the pneumococcal vaccines Pneumovax, Prevnar7, and Prevnar13, which substantially reduced the S. pneumoniae disease burden in developed...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Su, Huali, Liu, Qing, Bian, Xiaoping, Wang, Shifeng, Curtiss, Roy, Kong, Qingke
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812815/
https://ncbi.nlm.nih.gov/pubmed/33380455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013350118
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